The Vasculome: From Many One – Ebook PDF Instant Delivery – ISBN(s): 9780128225462,0128225467
Product details:
- ISBN-10 : 0128225467
- ISBN-13 : 978-0128225462
- Author: Zorina S. Galis
The Vasculome: From Many, One introduces the fundamental bases of the “unity in diversity of the Vasculome, from the coming together of various cell lineages during development, to its deceptively simple solution for architectural design: the efficient interplay of a few types of building blocks supporting key similar functions throughout the body and their highly specialized functional local variations. Specific examples are included to illustrate how the Vasculome is integral to the function and malfunction of different organs, such as the brain or the kidney.
Table contents:
Chapter 1. Development of, and environmental impact on, endothelial cell diversity
Chapter 2. Endothelial cell heterogeneity and plasticity in health and disease—new insights from single-cell studies
Chapter 3. The remarkable diversity of vascular smooth muscle in development and disease: a paradigm for mesenchymal cell types
Chapter 4. Smooth muscle diversity in the vascular system
Chapter 5. Resident vascular immune cells in health and atherosclerotic disease
Chapter 6. Perivascular adipose tissue: friend or foe?
Chapter 7. Major vascular ECM components, differential distribution supporting structure, and functions of the vasculome
Chapter 8. Out to the tissues: the arterial side (arteries, arterioles—development, structure, functions, and pathologies)
Chapter 9. Capillary diversity: endothelial cell specializations to meet tissue metabolic needs
Chapter 10. The neurovascular unit and blood–CNS barriers in health and disease
Chapter 11. Lymphatic biology and medicine
Chapter 12. The flow-dependent endotheliome: hemodynamic forces, genetic programs, and functional phenotypes
Chapter 13. Intravital photoacoustic microscopy of microvascular function and oxygen metabolism
Chapter 14. Systems biology modeling of endothelial cell and macrophage signaling in angiogenesis in human diseases
Chapter 15. Simulation of blood flow and oxygen transport in vascular networks
Chapter 16. Clinical investigations of vascular function
Chapter 17. Angiodiversity—A tale retold by comparative transcriptomics
Chapter 18. Using pattern recognition and discriminant analysis of functional perfusion data to create “angioprints” for normal and perturbed angiogenic microvascular networks
Chapter 19. Artificial intelligence for the vasculome
Chapter 20. Vascular development and organogenesis: depots of diversity among conduits of connectivity define the vasculome
Chapter 21. Normal vascular identity (arteries, veins, and lymphatics) and malformations
Chapter 22. Sprouting angiogenesis in vascular and lymphatic development
Chapter 23. Enablers and drivers of vascular remodeling
Chapter 24. Extracellular matrix dynamics and contribution to vascular pathologies
Chapter 25. Lymphatic vascular anomalies and dysfunction
Chapter 26. Endothelial dysfunction: basis for many local and systemic conditions
Chapter 27. The vascular phenotype in hypertension
Chapter 28. Functional roles of lymphatics in health and disease
Chapter 29. Extracellular matrix genetics of thoracic and abdominal aortic diseases
Chapter 30. Peripheral arterial disease (pathophysiology, presentation, prevention/management)
Chapter 31. Venous diseases including thromboembolic phenomena
Chapter 32. Targeting vascular zip codes: from combinatorial selection to drug prototypes
Chapter 33. Angiosome concept for vascular interventions
Chapter 34. RNA therapies for cardiovascular disease
Chapter 35. The brain vasculome: an integrative model for CNS function and disease
Chapter 36. Vasculome: defining and optimizing vascular health
Chapter 37. The Vasculome provides a body-wide cellular positioning system and functional barometer. The “Vasculature as Common Coordinate Frame (VCCF)” concept
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