Practical Application of Supercritical Fluid Chromatography for Pharmaceutical Research and Development 1st Edition – eBook PDF
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Practical Application of Supercritical Fluid Chromatography for Pharmaceutical Research and Development – Ebook PDF
Practical Application of Supercritical Fluid Chromatography for Pharmaceutical Research and Development 1st Edition – Ebook PDF Instant Delivery – ISBN(s): 9780323884877,0323884873,9780323884884, 0323884881
Product details:
- ISBN-10 : 0323884873
- ISBN-13 : 978-0323884877
- Author: Dr. Michael Hicks
Practical Application of Supercritical Fluid Chromatography for Pharmaceutical Research and Development provides a valuable “go-to reference for many difficult-to-solve challenges using pertinent chromatographic theory, first-hand case studies, and examples provided from academic and industry experts. This text also enables professors teaching an analytical instrumental course to introduce and instruct students about one of the most sustainable and powerful separation methods currently available. While the text has broad applicability across industrial sectors, it focuses primarily on application in the pharmaceutical industry. The book is designed to allow readers to align current HPLC/UHPLC capabilities with SFC as an orthogonal tool for project specific methods in the pharmaceutical industry. It highlights where SFC falls on the spectrum of useful chromatographic tools for routine and challenging separative methods.
Table contents:
1. Application space for SFC in pharmaceutical drug discovery and development
2. Evolution and history of SFC as greener preparative Tool
3. SFC for chiral resolution of pharmaceuticals
4. Advantages of new column technologies with SFC
5. Synthetic and process chemistry reaction screening
6. Method development approaches for small molecule analytes
7. Expanding the boundaries of SFC: starting materials, excipients, lipidated peptide conjugates, PEGs
8. Application driven detection
9. Advantages of SFC – over historical and compendial normal phase methods
10. Peptides, proteins and the use of water with SFC methods
11. Other miscellaneous applications of SFC as a sustainable analytical tool, nucleic acids and sugars
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