Phytochemicals as Lead Compounds for New Drug Discovery: Prospects for Sustainable Agriculture – Ebook PDF Instant Delivery – ISBN(s): 9780128178904,0128178906

Product details:

• ISBN-10 ‏ : ‎ 0128178906
• ISBN-13 ‏ : ‎ 978-0128178904
• Author: Chukwuebuka Egbuna, Shashank Kumar, Jonathan C. Ifemeje, Shahira M. Ezzat, Saravanan Kaliyaperumal

Phytochemicals as Lead Compounds for New Drug Discovery presents complete coverage of the recent advances in the discovery of phytochemicals from medicinal plants as models to the development of new drugs and chemical entities. Functional bioactive compounds of plant origin have been an invaluable source for many human therapeutic drugs and have played a major role in the treatment of diseases around the world. These compounds possess enormous structural and chemical diversity and have led to many important discoveries. This book presents fundament concepts and factors affecting the choice for plant-based products, as well as recent advances in computer-aided drug discovery and FDA drug candidacy acceptance criteria. It also details the various bioactive lead compounds and molecular targets for a range of life-threatening diseases including cancer, diabetes, and neurodegenerative diseases.

Table contents:

1. Plant secondary metabolites as lead compounds for the production of potent drugs
2. Factors affecting the choice for plant-based products in drug discoveries
3. Advances in computer-aided drug discovery
4. FDA drug candidacy acceptance criteria and steps: problems and way forward
5. Bioactive lead compounds and molecular targets for the treatment of heart diseases
6. Natural bioactive lead compounds effective against haematological malignancies
7. Adjunct therapeutic potential of phytochemicals against cancer
8. Antidiabetic lead compounds and targets for drug development
9. Antiobesity functional leads and targets for drug development
10. Phytochemicals as therapeutic interventions in neurodegenerative diseases
11. Organosulfur phytochemicals against metabolic and neurodegenerative diseases: benefits and risks
12. Lead compounds with the potentials for the treatment of chronic liver diseases
13. Bioactive lead compounds effective against skin diseases
14. Phytochemicals as emerging therapeutic agents for alopecia treatment
15. Antiviral phytocompounds for drug development: a data mining studies
16. Shikimic acid as intermediary model for the production of drugs effective against influenza virus
17. Antimicrobial lead compounds from marine plants
18. Antibacterial lead compounds and their targets for drug development
19. Awareness and current therapeutic strategies of malaria
20. Bioactive lead compounds and targets for the development of antimalarial drugs
21. Bioactive lead compounds and molecular targets for the development of antiinflammatory drugs
22. Functional lead compounds and targets for the development of drugs for the treatment of male infertility
23. Prenylated flavonoids as a promising drug discovery candidate: a pharmacological update
    

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