Molecular Nutrition and Mitochondria: Metabolic Deficits, Whole-Diet Interventions, and Targeted Nutraceuticals 1st Edition – Ebook PDF Instant Delivery – ISBN(s): 9780323902564,0323902561, 9780323984522, 0323984525
Product details:
- ISBN-10 : 0323984525
- ISBN-13 : 9780323984522
- Author:
Molecular Nutrition and Mitochondria: Metabolic Deficits, Whole-Diet Interventions, and Targeted Nutraceuticals provides a comprehensive examination of molecular aspects of mitochondrial nutrition and how dietary compounds might impact the treatment of mitochondrial dysfunction.
Beginning with an overview of the fundamentals of mitochondria physiology and the methods used to evaluate mitochondrial imbalance in clinical practice, the book goes on to outline nutritional shortfalls in mitochondrial dysfunction and highlights the complex intra-organelle milieu affecting interactions between food compounds and mitochondrial co-factors, metabolites, and signaling molecules. Further sections explore the impact of essential nutrients, such as vitamin E, fatty acids, and complex lipids, on mitochondrial biogenesis, as well as non-essential bioactive compounds originating from food that can be evaluated for their mitochondria-modulating potential, such as mitochondria-targeted small molecule antioxidants, plant-based pigments and organic compounds, nucleotides, non-proteogenic amino acids and derivatives, and mitochondria-specific enzyme mimetics from food.
Molecular Nutrition and Mitochondria covers the key impacts of nutrition on mitochondria, and is the ideal reference for researchers, students and clinicians looking to develop an in-depth understanding of how dietary compounds can prevent and treat disorders associated with mitochondrial dysfunction.
Table contents:
Section 1: Mitochondria as a target in experimental and clinical nutrition
Chapter 1 – Targeting mitochondrial dysfunction with nutrients: challenges and opportunities
Chapter 2 – Mitochondrion at the crossroads between nutrients and the epigenome
Chapter 3 – Nutritional assessment and malnutrition in adult patients with mitochondrial disease
Chapter 4 – Therapeutic potential and metabolic impact of alternative respiratory chain enzymes
Section 2: Essential nutrients in mitochondrial nutrition
Chapter 5 – Aging, mitochondrial dysfunctions, and vitamin E
Chapter 6 – The role of B vitamins in protecting mitochondrial function
Chapter 7 – Analysis of the mitochondrial status of murine neuronal N2a cells treated with resveratrol and synthetic isomeric resveratrol analogs: aza-stilbenes
Chapter 8 – Dietary eicosapentaenoic acid and docosahexaenoic acid for mitochondrial biogenesis and dynamics
Chapter 9 – Vitamin C and mitochondrial function in health and exercise
Chapter 10 – Roles of dietary fiber and gut microbial metabolites short-chain fatty acids in regulating mitochondrial function in central nervous system
Section 3: Dietary bioactive compounds and mitochondrial function
Chapter 11 – Mitochondria-targeted antioxidants: coenzyme Q10, mito-Q and beyond
Chapter 12 – Flavonoids, mitochondrial enzymes and heart protection
Chapter 13 – Tea polyphenols stimulate mt bioenergetics in cardiometabolic diseases
Chapter 14 – A review of quercetin delivery through nanovectors: cellular and mitochondrial effects on noncommunicable diseases
Chapter 15 – Creatine monohydrate for mitochondrial nutrition
Chapter 16 – Arginine and neuroprotection: a focus on stroke
Chapter 17 – Nutraceuticals for targeting NAD+ to restore mitochondrial function
Chapter 18 – Curcumin for protecting mitochondria and downregulating inflammation
Chapter 19 – Dihydrogen as an innovative nutraceutical for mitochondrial viability
Chapter 20 – Fucoxantin and mitochondrial uncoupling protein 1 in obesity
Chapter 21 – Rice bran extract for the prevention of mitochondrial dysfunction
Chapter 22 – Silymarin as a vitagene modulator: effects on mitochondria integrity in stress conditions
Chapter 23 – Buckwheat trypsin inhibitors: novel nutraceuticals for mitochondrial homeostasis
Section 4: Whole-diet interventions and mitochondrial function
Chapter 24 – Diet restriction-induced mitochondrial signaling and healthy aging
Chapter 25 – Rejuvenation of mitochondrial function by time-controlled fasting
Chapter 26 – Dietary modulation and mitochondrial DNA damage
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