Mitochondrial Intoxication 1st Edition – Ebook PDF Instant Delivery – ISBN(s): 9780323884624,0323884628, 9780323884631, 0323884636

Product details:

• ISBN-10 ‏ : ‎ 0323884636
• ISBN-13 ‏ : ‎ 9780323884631
• Author: Marcos Roberto de Oliveira PhD 

Mitochondrial Intoxication explores the effects toxic molecules can have upon mitochondrial physiology in the human body. Each chapter is dedicated to a specific toxicant, including pollutants, food additives, illicit and pharmaceutical drugs, and heavy metals. This book considers the implications and impact these have upon mitochondria and the diseases that can result from dysfunction and impairment in the human body. Furthermore, the book provides an overview of mitochondrial physiology and assesses the advances and challenges in testing mitochondrial toxicity. Case studies exploring mitochondrial intoxication in pregnancy and in the geriatric population are also included.

This is a comprehensive reference on the main toxicants impacting mitochondria in the human body, and the consequences this can have for health and disease.

• Features a wide range of toxicants and their effects on mitochondrial physiology
• Covers molecular markers of mitochondrial intoxication
• Includes case studies that illustrate the health impacts of toxicity upon mitochondria
• Considers future directions regarding the study of mitochondrial intoxication

Table of contents:

1. Mitochondrial physiology: An overview

2. Molecular markers of mitochondrial intoxication

3. Drug-induced mitochondrial impairment: Mechanisms and testing systems

4. Challenges in mitochondrial profiling during pre-clinical studies

5. Acrylamide

6. The effects of air pollution toxicants on the mitochondria

7. Aflatoxin B

8. The effects of the alcohol abuse against the mitochondria. Functional consequences for liver, muscle, and the brain

9. Aluminum

10. Discovery of amiodarone mitochondrial toxicity in liver and beyond

11. Ammonia

12. The mitochondrial disruption as a contributing factor for the neurotoxicity of amphetamines

13. Anthracycline

14. Antidepressants, mood stabilizing drugs and mitochondrial function; for better or for worse

15. The effects of antiretroviral drugs on the mitochondria

16. Arsenic

17. Mechanisms of bisphenol A toxicity in mitochondria

18. Chemotherapeutic drugs

19. Cuprizone

20. Delta‐9‐tetrahydrocannabinol (Cannabis sativa)

21. Diclofenac

22. Food additives

23. Mitochondria as a toxicological target for fungicides

24. The effects of methylglyoxal on the mitochondria

25. The effects of mercury on the mitochondria

26. Organohalogens

27. The effects of organophosphate pesticides on the mitochondria

28. Oxygen toxicity

29. Paracetamol/Acetaminophen

30. Plant molecules (Mitochondrial intoxication induced by plant molecules)

31. Polychlorinated biphenyls (PCBs)

32. The effects of polycyclic aromatic hydrocarbons on the mitochondria

33. Pyrethroids

34. Redox cycling compounds (Mitochondrial toxicity of redox cycling compounds)

35. The effects of sodium nitrate on the mitochondria

36. Zinc

People also search: