Introduction to Spatial Mapping of Biomolecules by Imaging Mass Spectrometry 1st edition – eBook PDF

Introduction to Spatial Mapping of Biomolecules by Imaging Mass Spectrometry – Ebook PDF Instant Delivery 1st edition – ISBN(s): 9780128189986,0128189983, 9780128189993, 0128189991

Product details:

• ISBN-10 ‏ : ‎0128189991
• ISBN-13 ‏ : ‎ 9780128189993
• Author: Bindesh Shrestha 

Imaging mass spectrometry (MS) techniques are often utilized without an understanding of their underlying principles, making it difficult for scientists to determine when and how they can exploit MS to visualize their biomolecules of interest. Introduction to Spatial Mapping of Biomolecules by Imaging Mass Spectrometry is an essential reference to help scientists determine the status and strategies of biomolecule analysis, describing its many applications for diverse classes of biomolecules.

The book builds a foundation of imaging MS knowledge by introducing ionization sources, sample preparation, visualization guidelines, molecule identification, quantification, data analysis, etc. The second section contains chapters focused on case studies on analyzing a biomolecule class of molecules. Case studies include an introduction/background, and a summary of successful imaging MS studies with illustrative figures and future directions.

Table of contents:

1. Fundamentals of Imaging Mass Spectrometry

2. Ionization Source for Imaging Mass Spectrometry

3. Sample Preparation and MALDI Matrix Applications

4. Tissue Sectioning for Imaging Mass Spectrometry

5. Matrix for Matrix-assisted Laser Desorption/Ionization (MALDI)

6. Molecule Identification Approaches in Imaging Mass Spectrometry

7. Quantitation Workflow in Imaging Mass Spectrometry

8. Spatial Resolution of Imaging Mass Spectrometry

9. Visualization of Imaging Mass Spectrometry

10. Analysis of imaging mass spectrometry data

11. Multimodal imaging mass spectrometry

12. Validation and Standardization of Imaging Mass Spectrometry

13. Towards Clinical Imaging Mass Spectrometry

14. Case study: Imaging N-Glycan on tissue

15. Case study: Reactive matrix and neurotransmitters and brain metabolites

16. Case study: Endogenous metabolites in mammalian tissues

17. Case study: Imaging of small drug molecules

18. Case study: Imaging Gangliosides

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