PART 1 The Profession of Medicine

1 The Practice of Medicine

2 Promoting Good Health

3 Vaccine Opposition and Hesitancy

4 Decision-Making in Clinical Medicine

5 Precision Medicine and Clinical Care

6 Screening and Prevention of Disease

7 Global Diversity of Health System Financing and Delivery

8 The Safety and Quality of Health Care

9 Diagnosis: Reducing Errors and Improving Quality

10 Racial and Ethnic Disparities in Health Care

11 Ethical Issues in Clinical Medicine

12 Palliative and End-of-Life Care

PART 2 Cardinal Manifestations and Presentation of Diseases

SECTION 1 Pain

13 Pain: Pathophysiology and Management

14 Chest Discomfort

15 Abdominal Pain

16 Headache

17 Back and Neck Pain

SECTION 2 Alterations in Body Temperature

18 Fever

19 Fever and Rash

20 Fever of Unknown Origin

SECTION 3 Nervous System Dysfunction

21 Syncope

22 Dizziness and Vertigo

23 Fatigue

24 Neurologic Causes of Weakness and Paralysis

25 Numbness, Tingling, and Sensory Loss

26 Gait Disorders, Imbalance, and Falls

27 Confusion and Delirium

28 Coma

29 Dementia

30 Aphasia, Memory Loss, and Other Cognitive Disorders

31 Sleep Disorders

SECTION 4 Disorders of Eyes, Ears, Nose, and Throat

32 Disorders of the Eye

33 Disorders of Smell and Taste

34 Disorders of Hearing

35 Upper Respiratory Symptoms, Including Earache, Sinus Symptoms, and Sore Throat

36 Oral Manifestations of Disease

SECTION 5 Alterations in Circulatory and Respiratory Functions

37 Dyspnea

38 Cough

39 Hemoptysis

40 Hypoxia and Cyanosis

41 Edema

42 Approach to the Patient with a Heart Murmur

43 Palpitations

SECTION 6 Alterations in Gastrointestinal Function

44 Dysphagia

45 Nausea, Vomiting, and Indigestion

46 Diarrhea and Constipation

47 Unintentional Weight Loss

48 Gastrointestinal Bleeding

49 Jaundice

50 Abdominal Swelling and Ascites

SECTION 7 Alterations in Renal and Urinary Tract Function

51 Interstitial Cystitis/Bladder Pain Syndrome

52 Azotemia and Urinary Abnormalities

53 Fluid and Electrolyte Disturbances

54 Hypercalcemia and Hypocalcemia

55 Acidosis and Alkalosis

SECTION 8 Alterations in the Skin

56 Approach to the Patient with a Skin Disorder

57 Eczema, Psoriasis, Cutaneous Infections, Acne, and Other Common Skin Disorders

58 Skin Manifestations of Internal Disease

59 Immunologically Mediated Skin Diseases

60 Cutaneous Drug Reactions

61 Photosensitivity and Other Reactions to Sunlight

SECTION 9 Hematologic Alterations

62 Interpreting Peripheral Blood Smears

63 Anemia and Polycythemia

64 Disorders of Granulocytes and Monocytes

65 Bleeding and Thrombosis

66 Enlargement of Lymph Nodes and Spleen

PART 3 Pharmacology

67 Principles of Clinical Pharmacology

68 Pharmacogenomics