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Handbook of Epigenetics : The New Molecular and Medical Genetics 3rd Edition Trygve O. Tollefsbol – eBook PDF

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Handbook of Epigenetics : The New Molecular and Medical Genetics – Ebook PDF

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Handbook of Epigenetics : The New Molecular and Medical Genetics – Ebook PDF Instant Delivery – ISBN(s): 9780323919098,9780323919500,032391909X,0323919502

Product details:

  • ISBN-10 ‏ : ‎ 032391909X
  • ISBN-13 ‏ : ‎ 978-0323919098
  • Author: Dr. Tollefsbol

Handbook of Epigenetics: The New Molecular and Medical Genetics, Third Edition provides a comprehensive analysis of epigenetics, from basic biology to clinical application. This new edition has been fully revised to cover the latest and evolving topics in epigenetics, with chapters updated and new chapters added on topics such as single-cell epigenetics, DNA methylation clocks in age-related diseases, transposable elements and epigenetics, X chromosome inactivation, and the epigenetics of drug addiction, among other topics. Throughout this edition, greater emphasis falls on epigenomic analyses and incorporating multi-omics approaches rather than gene-specific analyses.

In addition, this edition has also been enhanced with step-by-step instructions in research methods, as well as easy-to-digest disease case studies and clinical trials that provide context and applied examples of recent advances in disease understanding and epigenetic therapeutics. These features empower researchers to reproduce the approaches and studies discussed and aid clinical translation. Live links across chapters tie in relevant external datasets and resources.

Table contents:

Section I: Overview

Chapter 1. Epigenetics Overview
Section II: Molecular Mechanisms of Epigenetics
Chapter 2. Mechanisms of DNA Methylation and Demethylation During Mammalian Development
Chapter 3. Mechanisms of Histone Modifications
Chapter 4. The Epigenetics of Noncoding RNA
Chapter 5. Prions and prion-like phenomena in epigenetic inheritance
Chapter 6. Higher-order Chromatin Organization in Diseases, from Chromosomal Position Effect to Phenotype Variegation
Chapter 7. Polycomb-group proteins and epigenetic control of gene activity
Section III: Methods in Epigenetics
Chapter 8. Methods for Analyzing DNA Cytosine Modifications Genome-wide

Chapter 9. Genome-wide Analyses of Histone Modifications in the Mammalian

Chapter 10. Techniques for Analyzing Genome-wide Expression of Non-coding RNA

Chapter 11. Computational Epigenetics: The Competitive Endogenous RNAs

Section IV: Model Organisms of Epigenetics
Chapter 12. Epigenetic Mechanisms in Bacteria Bridge Physiology, Growth and Host–Pathogen Interactions
Chapter 13. Drosophila Epigenetics
Chapter 14. Models of Mouse Epigenetic Inheritance: Classification, Mechanisms, and Experimental Strategies
Chapter 15. Plant Epigenomics

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