Forensic Genetic Approaches for Identification of Human Skeletal Remains: Challenges, Best Practices, and Emerging Technologies 1st Edition – eBook PDF

Forensic Genetic Approaches for Identification of Human Skeletal Remains: Challenges, Best Practices, and Emerging Technologies 1st Edition – Ebook PDF Instant Delivery – ISBN(s): 9780128157664,9780128163696,0128157666,0128163690

Product details:

• ISBN-10 ‏ : ‎ 0128163690
• ISBN-13 ‏ : ‎ 9780128163696
• Author: Angie Ambers

Forensic Genetic Approaches for Identification of Human Skeletal Remains: Challenges, Best Practices, and Emerging Technologies provides best practices on processing bone samples for DNA testing. The book outlines forensic genetics tools that are available for the identification of skeletal remains in contemporary casework and historical/archaeological investigations. Although the book focuses primarily on the use of DNA for direct identification or kinship analyses, it also highlights complementary disciplines often used in concert with genetic data to make positive identifications, such as forensic anthropology, forensic odontology, and forensic art/sculpting.

Table contents:

1. Missing persons and unidentified human remains: The world’s silent mass disaster

2. Challenges in forensic genetic investigations of decomposed or skeletonized human remains: Environmental exposure, DNA degradation, inhibitors, and low copy number (LCN)

I. Guidelines and best practices for handling and processing human skeletal remains for genetic studies

3. Facilities design and workflow considerations for processing unidentified human skeletal remains

4. Location, recovery, and excavation of human remains for forensic testing

5. Skeletal microstructure, bone diagenesis, optimal sample selection, and pre-processing preparation techniques for DNA testing

6. DNA extraction methods for human skeletal remains

7. Quantitative and qualitative assessment of DNA recovered from human skeletal remains

II. Types of DNA markers and applications for identification

8. Autosomal short tandem repeat (STR) profiling of human

9. Y-chromosome analysis for unidentified human remains (UHR) investigations

10. Mitochondrial DNA and its use in the forensic analysis of skeletal material

11. X-chromosome short tandem repeats (X-STRs): Applications for human remains identification

12. Single nucleotide polymorphisms (SNPs): Ancestry-, phenotype-, and identity-informative SNPs

13. Diallelic Markers: INDELs and INNULs

III. Traditional platforms, alternative strategies, and emerging technologies for DNA analysis of human skeletal remains

14. Genotyping and sequencing of DNA recovered from human skeletal remains using capillary electrophoresis (CE)

15. Rapid DNA identification of human skeletal remains

16. Emerging technologies for DNA analysis of challenged samples

IV. Analysis of genetic data recovered from skeletonized human remains

17. Best practices in the development and effective use of a forensic DNA database for identification of missing persons and unidentified human remains

18. Software and database functionality for direct identification and kinship analysis: The Mass Fatality Identification System (M-FISys)

19. Bioinformatic tools for interrogating DNA recovered from human skeletal remains

20. The emerging discipline of forensic genetic genealogy

V. Complementary and multidisciplinary approaches to assist in identification of unidentified human skeletal remains

21. Forensic anthropology in a DNA world: How anthropological methods complement DNA-based identification of human remains

22. Generation of a personal chemical profile from skeletonized human remains

23. Forensic odontology: Historical perspectives and current applications for identification of human remains

24. Forensic facial reconstruction of skeletonized and highly decomposed human remains

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