(eBook PDF) Rowland and Tozer’s Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications 5th Edition – Digital Ebook – Instant Delivery Download

Product details:

• ISBN-10 ‏ : ‎ 1496385047
• ISBN-13 ‏ : ‎ 978-1496385048
• Author: Hartmut Derendorf Ph.D. (Author), Dr. Stephan Schmidt Ph.D (Author)

Updated with the latest clinical advances, Rowland and Tozer’s Clinical Pharmacokinetics and Pharmacodynamics, Fifth Edition, explains the relationship between drug administration and drug response, taking a conceptual approach that emphasizes clinical application rather than science and mathematics. Bringing a real-life perspective to the topic, the book simplifies concepts and gives readers the knowledge they need to better evaluate drug applications.

Table contents:

SECTION 1 BASIC CONSIDERATIONS 1
CHAPTER 1 Therapeutic Relevance 3
CHAPTER 2 Fundamental Concepts and Terminology 19

SECTION 2 EXPOSURE AND RESPONSE AFTER A SINGLE DOSE 51
CHAPTER 3 Kinetics Following an Intravenous Bolus Dose 53
CHAPTER 4 Membranes and Distribution 77
CHAPTER 5 Elimination 119
CHAPTER 6 Kinetics Following an Extravascular Dose 169
CHAPTER 7 Absorption 197
CHAPTER 8 Response 233

SECTION 3 THERAPEUTIC REGIMENS 265
CHAPTER 9 Therapeutic W indow 267
CHAPTER 10 Constant-Rate Input 283
CHAPTER 11 Multiple-Dose Regimens 319

SECTION 4 INDIVIDUALIZATION 359
CHAPTER 12 V ariability 361
CHAPTER 13 Genetics 393
CHAPTER 14 Age, W eight, and Gender 411
CHAPTER 15 Disease 443
CHAPTER 16 Nonlinearities 491
CHAPTER 17 Drug Interactions 531
CHAPTER 18 Initiating and Managing Therapy 577

SECTION 5 SUPPLEMENTAL TOPICS 611
CHAPTER 19 Distribution Kinetics 613
CHAPTER 20 Metabolites and Drug Response 657
CHAPTER 21 Protein Drugs 687
CHAPTER 22 Prediction and Refinement of Human Kinetics from In Vitro, Preclinical, and Early Clinical Data 731

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