From Globular Proteins to Amyloids – Ebook PDF Instant Delivery – ISBN(s): 9780081029817,0081029810
Product details:
- ISBN-10 : 0081029810
- ISBN-13 : 978-0081029817
- Author: Irena Roterman-Konieczna
From Globular Proteins to Amyloids proposes a model and mechanism for explaining protein misfolding. Concepts presented are based on a model originally intended to show how proteins attain their native conformations. This model is quantitative in nature and founded upon arguments derived from information theory. It facilitates prediction and simulation of the amyloid fibrillation process, also identifying the progressive changes that occur in native proteins that lead to the emergence of amyloid aggregations.
Table contents:
1. Description of the fuzzy oil drop model
2. Folding with the active participation of water
3. Information coded in protein structure
4. Glubular or ribbon-like micelle
5. Proteins structured as spherical micelles
6. Local discordance
7. Solenoid – amyloid under control
8. Composite structures
9. Permanent chaperons
10. Amyloids
11. Anti-amyloid drug design
12. Predicted structure of the transthyretin amyloid
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