A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery 6th Edition – Ebook PDF Instant Delivery – ISBN(s): 9780323992893,0323992897
Product details:
- ISBN-10 : 0323992897
- ISBN-13 : 978-0323992893
- Author: Terry P. Kenakin
A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, Sixth Edition features the latest research surrounding the application of pharmacology in drug discovery in an effort to equip readers with a deeper understanding of complex and rapid changes in this field. Written by well-respected pharmacologist, Terry P. Kenakin, this primer is an indispensable resource for anyone involved in drug discovery. This edition has been reorganized for better flow and clarity and includes material on new technologies for screening (virtual, DNA encoded libraires, fragment-based) and a major section on phenotypic (target agnostic) screening for new leads and determination of drug targets.
Table contents:
Chapter 1. What is pharmacology?
Chapter 2. How different tissues process drug response
Chapter 3. Drug–receptor theory
Chapter 4. Pharmacological assay formats: binding
Chapter 5. Drug targets and drug-target molecules
Chapter 6. Agonists: the measurement of affinity and efficacy in functional assays
Chapter 7. Orthosteric drug antagonism
Chapter 8. Allosteric modulation
Chapter 9. The optimal design of pharmacological experiments
Chapter 10. Pharmacokinetics
Chapter 11. Safety pharmacology
Chapter 12. The drug-discovery process
Chapter 13. Selected pharmacological methods
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